Magnesium and Dementia : Can magnesium intake prevent dementia?

Nutrition Corner with Dr D 

Magnesium and Dementia : Can magnesium intake prevent dementia?

Magnesium and dementia are two words that may not seem to be related, but a recent study has found that they could be the key to promoting good brain health and reducing the risk of cognitive decline. Dementia is the seventh biggest killer globally and the second leading cause of death in Australia. It's predicted that the number of people diagnosed with dementia will more than double by 2050. As there is no cure for dementia, prevention is the best course of action, and one way to do that is through diet.

Researchers from the Australian National University's National Centre for Epidemiology and Population Health conducted a study on over 6,000 cognitively healthy participants aged 40 to 73 in the United Kingdom. The study found that people who consume more than 550 milligrams of magnesium each day have a brain age that is approximately one year younger by the time they reach 55 compared to someone with a normal magnesium intake of about 350 milligrams a day.

 

Lead author and PhD researcher Khawlah Alateeq said, "Our study shows a 41 per cent increase in magnesium intake could lead to less age-related brain shrinkage, which is associated with better cognitive function and lower risk or delayed onset of dementia in later life." The researchers suggest that a higher intake of magnesium in our diets from a younger age may safeguard against neurodegenerative diseases and cognitive decline by the time we reach our 40s.

The study also found that the neuroprotective effects of more dietary magnesium appear to benefit women more than men and more so in post-menopausal than pre-menopausal women, although this may be due to the anti-inflammatory effect of magnesium.

 

The study highlights the potential benefits of a diet high in magnesium and the role it plays in promoting good brain health. The study's findings suggest that a diet rich in magnesium can have numerous benefits for brain health.

 

Benefits of Magnesium

Magnesium is a mineral that is essential for optimal brain function. The nervous system relies on magnesium to carry out many of its functions, including neurotransmitter release, synaptic plasticity, and oxidative stress regulation.

 

Neurotransmitters are chemicals that help to transmit signals in the brain. Magnesium plays a crucial role in regulating the release of these neurotransmitters, which helps to ensure that the brain can communicate effectively with other parts of the body.

 

Synaptic plasticity refers to the ability of synapses (the connections between neurons) to change and adapt over time. This is an important aspect of learning and memory, and magnesium is involved in this process.

 

Oxidative stress is a process that occurs when there is an imbalance between the production of reactive oxygen species (ROS) and the body's ability to detoxify them. This can lead to damage to cells and tissues, including those in the brain. Magnesium helps to regulate oxidative stress by acting as an antioxidant and protecting cells from damage.

 

Magnesium also helps to reduce inflammation, which is believed to contribute to neurodegenerative diseases such as dementia.

Magnesium and inflammation in the brain

Inflammation is the body's natural response to injury or infection, but chronic inflammation can cause damage to tissues and organs over time. It's believed that chronic inflammation in the brain plays a role in the development of neurodegenerative diseases such as dementia.

 

Magnesium is known to have anti-inflammatory properties and may help reduce inflammation in the brain. Inflammation in the brain can be caused by a variety of factors, such as chronic stress, poor diet, and lack of exercise. When inflammation is reduced, it can help protect brain cells and improve cognitive function.

 

Studies have shown that magnesium can help reduce inflammation in the brain by inhibiting the production of inflammatory molecules known as cytokines. Cytokines are produced by the immune system in response to infection or injury, but they can also contribute to chronic inflammation.

In addition to reducing inflammation, magnesium has been shown to improve brain function in other ways. For example, magnesium helps regulate the production of neurotransmitters, which are chemicals that transmit signals in the brain. Low levels of magnesium have been linked to lower levels of the neurotransmitter serotonin, which is associated with depression and anxiety.

 

Magnesium and cognitive function

Furthermore, magnesium is involved in the production of energy in brain cells, which is essential for optimal brain function. Studies have shown that magnesium can help improve cognitive function in older adults and may help protect against age-related cognitive decline.

 

Overall, the anti-inflammatory properties of magnesium may play an important role in promoting good brain health and reducing the risk of neurodegenerative diseases such as dementia. Incorporating magnesium-rich foods such as spinach, nuts, and whole grains into your diet may be an effective way to improve brain health and reduce the risk of cognitive decline.

Magnesium sources and supplements

The recommended daily intake of magnesium is between 310-420 mg for adults, with an average daily intake of around 300 mg for most people.

 

Magnesium can be found in a variety of foods, including spinach, nuts, legumes, seeds, and whole grains. These foods are rich in magnesium, with spinach containing around 157 mg of magnesium per cup, almonds containing 80 mg per ounce, and black beans containing 60 mg per half-cup serving.

 

In addition to a magnesium-rich diet, magnesium supplements can also be beneficial for brain health. However, not all forms of magnesium supplements are created equal. The most beneficial and biologically available form of magnesium supplement is magnesium glycinate, which is absorbed well by the body and does not cause digestive issues.

Conclusion

In conclusion, the study shows the potential benefits of a magnesium-rich diet in reducing the risk of cognitive decline and neurodegenerative diseases such as dementia. It suggests that people of all ages should be paying closer attention to their magnesium intake and incorporating magnesium-rich foods into their diets. Prevention is key in promoting good brain health, and a diet high in magnesium is one way to achieve that.

 

References 

Khawlah Alateeq, Erin I. Walsh, Nicolas Cherbuin. Dietary magnesium intake is related to larger brain volumes and lower white matter lesions with notable sex differences. European Journal of Nutrition, 2023; DOI: 10.1007/s00394-023-03123-x

 

Magnesium : Alzheimer Drug Discovery Foundation 

by Dr. Michal Domeny DNP, L.Ac, CD/N

Chronic Insomnia- The silent killer in your bedroom?

Medicine Corner with Dr D 

Insomnia: The Silent Killer in your Bedroom

Did you know that insomnia can have shocking effects on your health? Lack of sleep not only leaves you feeling tired and groggy but also weakens your immune system, makes it harder to control your blood pressure, and can even shorten your life span. In this article, we will delve deeper into the shocking truth of how insomnia affects your immune system and heart, and what you can do to combat it.

Insomnia and the Immune System

Insomnia has a profound impact on your immune system. When you don't get enough sleep, your body produces fewer cytokines, a type of protein that targets infection and inflammation, which makes it harder for your body to fight off diseases. This means that you are more susceptible to infections, including the common cold and flu, and even more severe illnesses such as cancer. Lack of sleep also affects the body's production of T-cells, which help fight off viruses and cancer cells, and can cause a decrease in the effectiveness of vaccines.

 

Insomnia and Heart

Insomnia can also have a devastating impact on your heart health. Poor sleep has been linked to an increased risk of cardiovascular disease, including hypertension, heart disease, and stroke. When you sleep, your blood pressure naturally lowers, but when you have insomnia, your blood pressure stays elevated, which puts a strain on your heart. Poor sleep can also lead to an increase in heart rate, which makes it harder to control your blood pressure even with medication. Snoring at night, which can be a sign of obstructive sleep apnea, can also make controlling blood pressure almost impossible.

Insomnia and Systemic Inflammation

But that's not all, chronic insomnia has been linked to increased inflammation in the body, which can contribute to a range of health problems. People with chronic insomnia have higher levels of inflammatory markers in their blood, such as C-reactive protein (CRP) and interleukin-6 (IL-6), compared to people who get adequate sleep. Insomnia disrupts the body's normal regulation of the stress response, which can lead to increased inflammation. Lack of sleep can activate the sympathetic nervous system (the body's fight or flight response) and the hypothalamic-pituitary-adrenal (HPA) axis, both of which are involved in the body's stress response. Chronic activation of these systems can lead to increased production of stress hormones, such as cortisol, and increased production of inflammatory markers.

 

Strategies to address insomnia

The effects of insomnia on your immune system and heart can be truly shocking, but there are things you can do to combat it. One of the most effective ways to improve your sleep is to establish a regular sleep routine. Try to go to bed and wake up at the same time every day, even on weekends. Create a relaxing environment in your bedroom, free of distractions like TV and phones.

Avoid Blue Lights

Blue light is a type of light that is emitted by electronic devices such as televisions, computers, and smartphones. Exposure to blue light in the evening can interfere with the body's natural production of melatonin, a hormone that helps regulate sleep-wake cycles. When we are exposed to blue light, it can suppress the production of melatonin, which can make it harder for us to fall asleep and stay asleep.

 

For this reason, it is recommended to avoid using electronic devices at least an hour before going to bed to reduce exposure to blue light. This can help prepare the body for sleep by allowing melatonin levels to rise naturally, which can promote feelings of sleepiness and help you fall asleep faster. Additionally, it's a good idea to dim the lights in your home in the hours leading up to bedtime to help the body produce more melatonin, signaling to the body that it's time for sleep.

To further promote healthy sleep habits, it's also recommended to establish a relaxing bedtime routine that can help signal to your body that it's time to wind down and prepare for sleep. This might include activities such as taking a warm bath, practicing relaxation techniques like deep breathing or meditation, or reading a book. By establishing a regular bedtime routine and avoiding exposure to blue light before bed, you can improve the quality of your sleep and promote better overall health and well-being. Practice relaxation techniques such as meditation, deep breathing, or yoga to help calm your mind and body. Avoid caffeine and alcohol, especially in the evening, as they can interfere with your sleep.

 

Conclusion

In conclusion, insomnia can have serious consequences for your health, particularly your immune system and heart. It can make it harder for your body to fight off infections and increase your risk of cardiovascular disease. It can also lead to increased inflammation in the body, which is linked to a range of health problems. Fortunately, there are steps you can take to improve your sleep and protect your health. By establishing a regular sleep routine, creating a relaxing sleep environment, practicing relaxation techniques, and avoiding caffeine and alcohol, you can improve the quality of your sleep and reduce your risk of health problems associated with insomnia. If you continue to struggle with insomnia, it's important to talk to your healthcare provider, who can help you identify underlying causes and develop a treatment plan to improve your sleep and overall health.

by Dr. Michal Domeny DNP, L.Ac, CD/N