Leaky gut: What is it, and how does it affect you?

Medicine Corner with Dr D 

Leaky gut: What is it, and how does it affect you?

In the mysterious realm of our bodies, the gut takes on the role of an enigmatic maestro, conducting a complex symphony of microorganisms and physiological processes. Once brushed aside by modern medicine, the gut's potential influence on our overall health is now emerging as a fascinating and vital topic of investigation. The ancient belief that imbalances within the stomach could cause illness, once deemed obsolete, is now being revisited as new discoveries suggest a link between a dysfunctional gastrointestinal system and various chronic diseases prevalent in today's society.

Enter the intriguing world of "leaky gut," a term gaining momentum in medical discussions and online forums. This relatively new concept, which explores the impact of increased intestinal permeability, has piqued the interest of researchers and medical professionals alike. As we delve into the depths of the gut, we will uncover its fascinating secrets, its potential effects on our health, and the steps we can take to foster a healthier gastrointestinal system.

Prior to advancements in medical knowledge regarding disease-causing mechanisms, physicians believed that certain illnesses could arise from imbalances within the stomach, referring to this as hypochondriasis. Derived from Ancient Greek, "hypochondrium" refers to the upper abdomen, the area between the breastbone and navel. As science progressed, this concept was dismissed, and the term "hypochondriac" came to describe individuals with a constant, often baseless fear of serious medical conditions.

 

However, is it possible that the ancient notion of illnesses originating in the gut holds some merit? Could various chronic diseases prevalent in society today be connected to a dysfunctional gastrointestinal system?

What is “leaky gut”?

The term "leaky gut" has been gaining traction in medical blogs and social media, although it may not be familiar to many doctors. Also known as increased intestinal permeability, leaky gut is a relatively new concept primarily studied in basic sciences. Nevertheless, there is a growing interest in developing medications to counteract the effects of this issue.

 

So, what is leaky gut? Our intestines are lined with a vast intestinal lining that covers over 4,000 square feet of surface area. When functioning optimally, this lining forms a secure barrier, regulating what is absorbed into the bloodstream. An unhealthy gut lining may have significant cracks or openings, enabling partially digested food, toxins, and microorganisms to infiltrate the underlying tissues. This infiltration may lead to inflammation, changes in gut flora (normal bacteria), and potential issues within the digestive tract and beyond. Current research is thriving, with studies suggesting that alterations in intestinal bacteria and inflammation might contribute to the development of numerous chronic diseases.

Modern lifestyles may be the primary contributor to gut inflammation. Emerging evidence suggests that the typical American diet, low in fiber and high in sugar and saturated fats, may trigger this process. Excessive alcohol consumption and stress also appear to impact this balance.

 

Who is affected by leaky gut and why?

Everyone experiences some degree of leaky gut, as the intestinal barrier is not entirely impervious (nor should it be). Some individuals may possess a genetic predisposition, making them more susceptible to alterations in the digestive system, but genetics alone are not the sole factor.

It is well-established that increased intestinal permeability plays a role in gastrointestinal conditions such as celiac disease, Crohn's disease, and irritable bowel syndrome. The primary question is whether leaky gut can cause issues elsewhere in the body. Some research indicates associations between leaky gut and other autoimmune diseases (lupus, type 1 diabetes, multiple sclerosis), chronic fatigue syndrome, fibromyalgia, arthritis, allergies, asthma, acne, obesity, and even mental illness. However, causal relationships have not yet been established through human clinical studies.

 

Towards a healthier gut:

Although "increased intestinal permeability" is not a common term in most doctor's offices, alternative and integrative medicine practitioners have focused on gut healing as an initial step in treating chronic diseases for years. Various cultures around the world often recommend specific diets for improved health. Even in the United States, dietary changes are common after illness. Many practitioners begin by eliminating inflammatory foods and those that may disrupt gut flora, such as alcohol, processed foods, certain medications, and any allergenic or sensitivity-causing foods.

 

There is still controversy over whether leaky gut contributes to the development of diseases outside the gastrointestinal tract in humans. However, consuming a nutritious, unprocessed diet that includes anti-inflammatory foods (and avoids inflammation-triggering foods) may, in theory, help repair the gut lining and restore balance to gut flora. This approach could lead to improved health without adverse side effects, making it worth considering.

by Dr. Michal Domeny DNP, L.Ac, CD/N

Dark Chocolate : Who Should Avoid Eating Dark Chocolate?

Nutrition Corner with Dr D 

Dark Chocolate: Who Should Avoid Eating Dark Chocolate?

Who shouldn't eat dark chocolate? You might be surprised to learn that despite its many touted health benefits, dark chocolate isn't for everyone. While it's true that consuming moderate amounts of dark chocolate can help reduce the risk of heart disease, lower blood pressure, and improve cognitive function, there are certain groups of people who should avoid eating it altogether. In this article, we'll explore the dark side of dark chocolate and reveal which surprising groups of people should steer clear of this indulgent treat.

II. Dark chocolate and caffeine sensitivity

 

Caffeine is a stimulant that affects the central nervous system and can have both positive and negative effects on the body. While many people enjoy the energy boost that comes from consuming caffeine, others can be highly sensitive to its effects. The degree of caffeine sensitivity can vary widely between individuals, with some people experiencing negative side effects even at relatively low doses.

 

Some individuals may be more sensitive to caffeine due to genetic factors, while others may be more sensitive due to lifestyle factors such as sleep habits or stress levels. Other factors such as age, weight, and overall health can also play a role in determining an individual's sensitivity to caffeine.

 

Dark chocolate, which contains both caffeine and other stimulants such as theobromine, can exacerbate caffeine sensitivity in some individuals. In fact, studies have linked dark chocolate consumption to negative caffeine effects such as increased heart rate, jitteriness, and insomnia.

 

One study published in the Journal of Caffeine Research found that even small amounts of dark chocolate can significantly increase caffeine levels in the blood, leading to greater caffeine sensitivity. This effect was especially pronounced in individuals who were already highly sensitive to caffeine.

 

Another study published in the Journal of Psychopharmacology found that consuming dark chocolate before bed can interfere with sleep quality, due to the caffeine and other stimulants in the chocolate. This can lead to daytime fatigue and other negative consequences for overall health and wellbeing.

 

 III. Dark Chocolate and Migraines

 

Migraines are a type of headache that can cause severe pain, nausea, and sensitivity to light and sound. While the exact causes of migraines are not fully understood, certain foods have been known to trigger them in some individuals. Dark chocolate is one such food that has been identified as a potential migraine trigger.

 

The link between migraines and certain foods is well-established, with research suggesting that up to 60% of migraine sufferers may have food triggers. Foods that commonly trigger migraines include aged cheese, processed meats, and alcohol. Dark chocolate has also been identified as a potential trigger due to its high levels of tyramine and phenylethylamine.

 

Tyramine is a naturally occurring amino acid that is found in high-protein foods that have been aged, fermented, or stored for long periods of time. Phenylethylamine, on the other hand, is a naturally occurring chemical that is found in chocolate and has been shown to affect blood flow in the brain. Both of these compounds are thought to contribute to the development of migraines in susceptible individuals.

 

Several studies have examined the link between dark chocolate and migraines, with some suggesting that dark chocolate consumption may increase the risk of migraines in certain individuals. One study published in the Journal of Headache and Pain found that dark chocolate was a trigger for migraines in 22% of migraine sufferers who participated in the study. Another study published in the Journal of Oral Rehabilitation found that dark chocolate consumption was associated with an increased risk of headaches in individuals with temporomandibular disorders.

 

It is important to note that not all individuals with migraines will be sensitive to dark chocolate, and some may be able to consume it without experiencing any negative effects. However, for those who do experience migraines triggered by dark chocolate, avoiding it may be necessary to manage their condition.

IV. Dark Chocolate and Irritable Bowel Syndrome (IBS)

 

Irritable bowel syndrome (IBS) is a common gastrointestinal disorder that affects millions of people worldwide. The condition is characterized by chronic abdominal pain, bloating, and changes in bowel habits, including diarrhea and constipation. While there is no known cure for IBS, there are several dietary and lifestyle changes that can help manage its symptoms.

 

However, for individuals with IBS, certain foods can exacerbate symptoms and trigger flare-ups. One such food is dark chocolate, which contains high levels of caffeine and a compound called theobromine. Caffeine is a stimulant that can increase the activity of the gastrointestinal tract, leading to diarrhea and abdominal cramps, both common symptoms of IBS. Theobromine, on the other hand, can relax the smooth muscles in the gut, leading to constipation.

 

 

Several studies have linked the consumption of dark chocolate to the exacerbation of IBS symptoms. In one study, participants with IBS were given either a high or low dose of theobromine, the active compound in chocolate. The results showed that those who received the higher dose experienced more severe symptoms, including bloating, abdominal pain, and constipation. Another study found that the consumption of chocolate, including dark chocolate, was associated with an increased risk of developing IBS symptoms.

It's important to note that not everyone with IBS will experience symptoms after consuming dark chocolate. However, for those who do, it's best to avoid or limit their intake of chocolate and other foods high in caffeine and theobromine, such as coffee and tea.

 

V. Dark Chocolate and Acid Reflux

Dark chocolate is often considered a guilty pleasure by many, but for individuals who suffer from acid reflux, it may be best to avoid it altogether. Acid reflux, also known as gastroesophageal reflux disease (GERD), is a common digestive disorder characterized by the backward flow of stomach acid into the esophagus. Symptoms of acid reflux include heartburn, regurgitation, chest pain, difficulty swallowing, and a sour taste in the mouth.

 

The main cause of acid reflux is a weakened lower esophageal sphincter (LES), a muscle that acts as a barrier between the stomach and the esophagus. When the LES fails to close properly, stomach acid can leak back into the esophagus, leading to symptoms of acid reflux. Certain foods and drinks can trigger acid reflux by relaxing the LES, including chocolate, caffeine, and fatty or spicy foods.

 

Dark chocolate is a known trigger for acid reflux. The high fat content in dark chocolate can cause the LES to relax, allowing stomach acid to flow back into the esophagus. Additionally, dark chocolate contains methylxanthines, which are compounds found in coffee and tea that can also trigger acid reflux by relaxing the LES.

 

Studies have identified dark chocolate as a potential trigger for acid reflux. In a study published in the American Journal of Gastroenterology, researchers found that dark chocolate caused a significant increase in acid reflux symptoms compared to a placebo. Another study published in the Journal of Clinical Gastroenterology found that dark chocolate had a higher potential for triggering acid reflux compared to milk chocolate.

 

Individuals who suffer from acid reflux should limit their intake of dark chocolate or avoid it altogether. Instead, they can opt for low-fat or fat-free desserts, such as sorbet or fruit, and choose beverages that are less likely to trigger acid reflux, such as water or herbal tea.

VI Dark Chocolate and Kidney Disease

Kidney disease is a serious health condition that affects the function of the kidneys. The kidneys are responsible for filtering the blood, removing waste products and excess fluid from the body, and regulating electrolyte balance.

 

When the kidneys are damaged, they are not able to perform these functions properly, leading to a buildup of waste products and fluids in the body. Dark chocolate, which is rich in oxalates, can be harmful for individuals with kidney disease.

 

Oxalates are compounds that can form crystals in the urine and lead to the development of kidney stones. A study published in the Clinical Journal of the American Society of Nephrology found that dietary intake of oxalates was associated with an increased risk of kidney stones in women with a history of kidney stones.

 

In addition to its oxalate content, dark chocolate also contains high levels of potassium and phosphorus, which can be problematic for individuals with kidney disease.

The kidneys are responsible for regulating the levels of these minerals in the body, and when the kidneys are not functioning properly, excess levels of potassium and phosphorus can build up in the blood, leading to complications such as bone disease, muscle weakness, and abnormal heart rhythms.

 

A study published in the American Journal of Clinical Nutrition found that high intake of dietary potassium was associated with an increased risk of kidney function decline in older adults. Similarly, a study published in the Journal of Renal Nutrition found that a diet high in phosphorus was associated with an increased risk of mortality in individuals with kidney disease.

 

It is important to note that these effects are mostly seen in individual who already have impaired kidney function as evidenced by decreased Glomerular Filtration Rate (GFR).

 

Conclusion

In conclusion, dark chocolate is a delicious treat that has many health benefits, but it may not be suitable for everyone. As we have discussed, certain groups of people should avoid consuming dark chocolate due to its potential negative effects on their health.

 

Individuals with acid reflux, irritable bowel syndrome, and kidney disease should be cautious about consuming dark chocolate as it can exacerbate their symptoms and potentially worsen their condition. In addition, pregnant women should also limit their consumption of dark chocolate due to its caffeine content.

 

However, for those who can enjoy dark chocolate without adverse effects, it can be a part of a healthy diet in moderation. Dark chocolate is rich in antioxidants and can help improve heart health, brain function, and lower the risk of certain diseases.

 

It is important to note that while dark chocolate does have health benefits, it should not be consumed in excess. Like any other food, moderation is key. Enjoying a small amount of dark chocolate as a treat can be a part of a healthy and balanced diet.

 

In summary, while dark chocolate is a delicious and beneficial treat, it is not suitable for everyone. Individuals with certain health conditions and pregnant women should be cautious about consuming dark chocolate. However, for those who can enjoy it in moderation, dark chocolate can be a part of a healthy diet.

by Dr. Michal Domeny DNP, L.Ac, CD/N